During which of the following phases of meiosis do centromeres split and sister chromatids migrate to opposite poles of the cell?
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Meiosis-- Movie Narrative (Advanced Look) Show
Many organisms pass their genes to their offspring through sexual reproduction. This begins when two gametes unite to form an embryo that is genetically unique from the parent organisms. The embryo then grows into an adult who in turn passes their genetic information on to their offspring. Gametes are formed through a process called meiosis. The cells that undergo meiosis to produce the gametes are called germ-line cells. In diploid organisms, germ-line cells have two copies of each chromosome. Germ-line cells undergo meiosis to produce haploid gametes which have only one copy of each chromosome. These haploid gametes fuse to form a diploid embryo that grows into the adult. Meiosis is just one step in the life cycle of a germ-line cell. Similar to mitosis, the cells also pass through the interphase, G1, S, and G2 stages before they enter meiosis. The DNA inside a germ-line cell is duplicated before meiosis begins during the S phase. The duplicated germ-line chromosomes are called sister chromatids. These chromatids remain attached to each other until the second cell division event in meiosis. There are two cell division events during meiosis. The first division, meiosis I, results in two unique daughter cells that have half the amount of DNA as the parent germ-line cell. The second division, meiosis II, results in four unique haploid cells that only have one copy of each chromosome. These haploid cells are the gametes that could go on to produce an offspring through sexual reproduction. Let’s look more closely at each of the division events. Meiosis begins with prophase I. In this stage, the DNA condenses to form chromosomes. Here we see the duplicated sister chromatids joined together at the centromere. They stay fused at the centromere throughout Meiosis I. Next, each pair of homologous chromosomes undergoes synapsis to form a complex involving two pairs of sister chromatids. Chromosomal material is exchanged between the two pairs of sister chromatids. This event is called recombination or more commonly, crossing over. After crossing over, the sister chromatids for each chromosome are no longer identical to one another. This is one of the reasons why no two siblings (aside from twins) are genetically identical. There are several more key steps in prophase I. The nuclear membrane begins to break down. Then the two centrosomes migrate to opposite ends of the cell and microtubules appear. The microtubules then attach to the chromosomes. The next phase of meiosis I is called metaphase I. Here the synapsed chromosomes align at the equator of the cell. The chromosomes align randomly which results in different combinations each time meiosis occurs. The next phase is anaphase I. During this phase, homologous chromosomes separate and migrate to the two poles of the cell. Importantly, the sister chromatids remain attached at their centromeres. The final steps of meiosis I are telophase I and cytokinesis. Here the cell divides into two daughter cells. Each of these two cells now undergo meiosis II. Meiosis II is similar to mitosis. The first stage of meiosis II is prophase II. Again, chromosomes condense, the nuclear envelop breaks down, and the spindle apparatus forms. The major difference between prophase II and prophase I is the fact that the daughter cells have only one copy of each homologous chromosome. So, in prophase II, there is no synapsis of homologous chromosomes or crossing over. In metaphase II, the chromosomes align at the equator of the cell. Again, the alignment is random. Since the sister chromatids are no longer identical, there will be many different possible ways for these chromosomes to align. In anaphase II, the sister chromatids are pulled apart as the microtubules shorten. Also, the ends of the cell are pushed further apart as microtubules elongate. In telophase II, the nuclear membrane reforms, and the cytoplasm is divided into the two haploid daughter cells. This division is called cytokinesis. Since meiosis II began with two cells, and each of those cells were split into two cells, we now have 4 unique haploid cells at the end of meiosis. These cells are gametes. Two gametes, one from the father and one from the mother, may fuse to produce a diploid embryo. The resulting embryo then grows through many cycles of mitosis. Understanding: • Homologous chromosomes separate in meiosis I • Sister chromatids separate in meiosis II
The first meiotic division is a reduction division (diploid → haploid) in which homologous chromosomes are separated
The second division separates sister chromatids (these chromatids may not be identical due to crossing over in prophase I)
The final outcome of meiosis is the production of four haploid daughter cells
Meiosis Overview Animation of the Stages of Meiosis During which phase do the centromeres split and sister chromatids move to the poles?The correct option is B Anaphase. Anaphase stage is characterized by the following key events: Centromeres split and chromatids separate. Chromatids move to opposite poles.
During which of the following phases of meiosis do centromeres separate and sister chromatids migrate to opposite poles of the cell?Anaphase. The shortest stage of mitosis. The centromeres divide, and the sister chromatids of each chromosome are pulled apart - or 'disjoin' - and move to the opposite ends of the cell, pulled by spindle fibres attached to the kinetochore regions.
During which phase of meiosis does centromere split?Which of the following stages of meiosis involves the division of centromere? Explanation: It is during the anaphase, the centromeres divide. The chromatids begin to move towards the two opposite poles.
In which phase of meiosis do the chromosomes separate at their centromeres with chromatids migrating to the poles?The chromosomes align at the center of the cell, and spindle fibers connect to the centromere of each chromosome and extend to centrioles at the 2 poles of the mitotic figure. Inanaphase the chromosomes divide along their longitudinal axes to form 2 daughter chromatids, which then migrate to opposite poles of the cell.
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